Zhi-Nan Chen Selected Research

Inflammasomes

6/2022

Blockade of mIL-6R alleviated lipopolysaccharide-induced systemic inflammatory response syndrome by suppressing NF-κB-mediated Ccl2 expression and inflammasome activation.

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Zhi-Nan Chen Research Topics

Disease

84	Neoplasms (Cancer) 03/2024 - 09/2003
52	Hepatocellular Carcinoma (Hepatoma) 01/2022 - 06/2000
33	Neoplasm Metastasis (Metastasis) 01/2022 - 09/2003
9	Lung Neoplasms (Lung Cancer) 01/2021 - 06/2010
6	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 02/2022 - 11/2017
6	Pancreatic Neoplasms (Pancreatic Cancer) 12/2020 - 12/2013
5	Inflammation (Inflammations) 01/2024 - 03/2011
5	Infections 12/2022 - 04/2009
5	Carcinogenesis 01/2019 - 01/2015
4	Liver Neoplasms (Liver Cancer) 03/2024 - 09/2014
4	COVID-19 01/2023 - 12/2020
4	Fibrosis (Cirrhosis) 11/2022 - 02/2007
3	Colitis 01/2023 - 01/2015
3	Rheumatoid Arthritis 01/2022 - 01/2005
3	Carcinoma (Carcinomatosis) 01/2015 - 05/2009
2	Virus Diseases (Viral Diseases) 12/2022 - 12/2020
2	Pulmonary Fibrosis (Fibrosing Alveolitis) 11/2022 - 11/2022
2	Hematologic Neoplasms (Hematological Malignancy) 02/2022 - 01/2019
2	Colitis-Associated Neoplasms 01/2022 - 01/2015
2	Experimental Arthritis 01/2022 - 01/2018
2	Colorectal Neoplasms (Colorectal Cancer) 01/2022 - 09/2006
2	Pneumonia (Pneumonitis) 01/2021 - 01/2021
2	Necrosis 01/2021 - 11/2019
2	Fatty Liver 01/2020 - 01/2020
2	Liver Cirrhosis (Hepatic Cirrhosis) 04/2018 - 12/2012
2	Breast Neoplasms (Breast Cancer) 11/2014 - 07/2013
2	Pathologic Processes 01/2013 - 11/2011
1	Hypoxia (Hypoxemia) 03/2024
1	Atherosclerosis 01/2024
1	Morphine Dependence 10/2023
1	Glioblastoma (Glioblastoma Multiforme) 06/2023
1	Autoimmune Diseases (Autoimmune Disease) 01/2023
1	Convalescence 01/2023

Drug/Important Bio-Agent (IBA)

22	Proteins (Proteins, Gene)FDA Link 12/2022 - 01/2005
15	AntigensIBA 03/2024 - 03/2004
15	Matrix Metalloproteinases (MMPs)IBA 03/2024 - 01/2005
10	Glycoproteins (Glycoprotein)IBA 01/2021 - 09/2006
10	Basigin (Extracellular Matrix Metalloproteinase Inducer (EMMPRIN))IBA 01/2018 - 08/2010
9	CytokinesIBA 01/2023 - 01/2019
8	Messenger RNA (mRNA)IBA 06/2023 - 03/2004
8	Monoclonal AntibodiesIBA 01/2021 - 06/2000
7	Biomarkers (Surrogate Marker)IBA 01/2022 - 05/2009
7	IntegrinsIBA 01/2018 - 01/2009
5	AntibodiesIBA 03/2024 - 06/2007
5	metuximabIBA 01/2022 - 06/2006
5	Immunoglobulins (Immunoglobulin)IBA 11/2019 - 02/2010
5	Annexin A2 (Annexin II)IBA 02/2016 - 02/2010
4	Chimeric Antigen ReceptorsIBA 08/2023 - 01/2019
4	meplazumabIBA 01/2023 - 01/2021
4	RNA (Ribonucleic Acid)IBA 11/2022 - 01/2011
4	ChemokinesIBA 01/2021 - 03/2011
4	LigandsIBA 11/2019 - 01/2018
4	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2015 - 06/2007
3	LipopolysaccharidesIBA 11/2022 - 01/2021
3	Therapeutic UsesIBA 01/2021 - 01/2018
3	Immunoconjugates (Immunoconjugate)IBA 11/2019 - 06/2000
3	Cisplatin (Platino)FDA LinkGeneric 01/2019 - 01/2017
3	Polysaccharides (Glycans)IBA 01/2018 - 09/2003
3	Small Interfering RNA (siRNA)IBA 07/2013 - 03/2007
3	Tumor Biomarkers (Tumor Markers)IBA 07/2009 - 05/2004
2	VaccinesIBA 06/2023 - 01/2018
2	Peptides (Polypeptides)IBA 01/2023 - 03/2003
2	LipidsIBA 12/2022 - 01/2022
2	Bleomycin (Blenoxane)FDA LinkGeneric 11/2022 - 11/2022
2	IronIBA 11/2022 - 01/2021
2	mu Opioid Receptors (mu Opioid Receptor)IBA 09/2022 - 01/2021
2	Immune Checkpoint InhibitorsIBA 01/2022 - 10/2019
2	Dextran SulfateIBA 01/2022 - 01/2015
2	Immunoglobulin G (IgG)IBA 01/2021 - 09/2006
2	Gemcitabine FDA Link 12/2020 - 09/2016
2	Oncogene Proteins (Oncogene Protein)IBA 09/2020 - 01/2017
2	Cadherins (E-Cadherin)IBA 01/2019 - 01/2018
2	MicroRNAs (MicroRNA)IBA 11/2018 - 01/2018
2	alpha-1,6-mannosylglycoprotein beta 1,6-N-acetylglucosaminyltransferaseIBA 01/2018 - 01/2013
2	CateninsIBA 01/2018 - 01/2015
2	Membrane Proteins (Integral Membrane Proteins)IBA 10/2015 - 06/2007
2	Carbon Tetrachloride (Tetrachloromethane)IBA 12/2012 - 04/2009
2	Metalloproteases (Metalloproteinases)IBA 01/2012 - 08/2010
2	alpha-Fetoproteins (alpha-Fetoprotein)IBA 06/2007 - 05/2004
2	DNA (Deoxyribonucleic Acid)IBA 01/2005 - 05/2004
1	azobenzeneIBA 03/2024
1	Complement System Proteins (Complement)IBA 03/2024
1	Apolipoproteins E (ApoE)IBA 01/2024
1	Morphine (MS Contin)FDA LinkGeneric 10/2023
1	Poly I-CIBA 06/2023
1	Cancer VaccinesIBA 06/2023
1	Hypochlorous Acid (Hypochlorite)IBA 06/2023
1	Neoplasm Antigens (Tumor Antigens)IBA 06/2023
1	AutoantibodiesIBA 01/2023
1	HLA-DR4 Antigen (HLA DR4 Antigen)IBA 01/2023
1	Cysteine (L-Cysteine)FDA Link 01/2023
1	Lactic Acid (Lactate)FDA LinkGeneric 01/2023
1	ClathrinIBA 12/2022
1	Deferoxamine (Desferal)FDA LinkGeneric 11/2022

Therapy/Procedure

26	Therapeutics 03/2024 - 11/2006
8	Immunotherapy 06/2023 - 01/2018
4	Radiotherapy 01/2020 - 04/2014
3	Drug Therapy (Chemotherapy) 01/2022 - 01/2015
3	Oncolytic Virotherapy 01/2018 - 07/2012
2	Radioimmunotherapy 11/2006 - 06/2006